Drug distribution in nanostructured lipid particles
نویسندگان
چکیده
منابع مشابه
Nanostructured Lipid Drug Carriers
solid lipid carriers – NLC. Particulate lipid matrices in the form of lipid pellets are known from the textbooks since many years, products are on the market (e. g. Mucosolvan retard, Boehringer-Ingelheim). After these lipid pellets as the first generation, P. Speiser developed so-called “lipid nanopellets for oral administration” in the middle of the eighties [1]. This system was not further d...
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During the past decade, the number of studies describing nanostructured lipid carriers (NLCs)-based formulations has been dramatically increased. The raise in NLC exploitation is essentially due to defeated barriers within the technological process of lipid-based nanoparticles' formulation and increased knowledge of the underlying mechanisms of transport of NLCs via different routes of administ...
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Development of delivery systems for new drug for its safe and effective delivery it into the body is an integral part of drug research program. This is particularly true due to increased incidence of adverse pharmacokinetic behavior of new drugs developed recently. Alternative delivery systems have been researched extensively not only to modulate their kinetic behavior in the body but also to a...
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Aim: Nano structured lipid carriers (NLCs) contains solid and liquid lipids as the significant principle in the drug delivery system. This review is focused on various aspects involved in the preparation, structure, advantages, limitations, types, physiochemical characterization and wide pharmaceutical applications of SLN has been explored. Method:It is revealed that NLCs proved to be a promisi...
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ژورنال
عنوان ژورنال: European Journal of Pharmaceutics and Biopharmaceutics
سال: 2017
ISSN: 0939-6411
DOI: 10.1016/j.ejpb.2016.10.008